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TM2-115

TM2-115
TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].
Catalog No. T9004Cas No. 1197196-47-6
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Purity:97.67%
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TM2-115

Catalog No. T9004Cas No. 1197196-47-6
TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$135In Stock
5 mg$313In Stock
10 mg$454In Stock
25 mg$687In Stock
50 mg$948In Stock
100 mg$1,270In Stock
1 mL x 10 mM (in DMSO)$369In Stock
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Product Introduction

Bioactivity
Description
TM2-115 is a inhibitor of malaria parasite histone methyltransferases that results in rapid and irreversible parasite death [1].
Chemical Properties
Molecular Weight490.64
FormulaC28H38N6O2
Cas No.1197196-47-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (91.71 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0382 mL10.1908 mL20.3815 mL101.9077 mL
5 mM0.4076 mL2.0382 mL4.0763 mL20.3815 mL
10 mM0.2038 mL1.0191 mL2.0382 mL10.1908 mL
20 mM0.1019 mL0.5095 mL1.0191 mL5.0954 mL
50 mM0.0408 mL0.2038 mL0.4076 mL2.0382 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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