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Anti-IL-19 Antibody (6K323) is a Mouse antibody targeting IL-19. Anti-IL-19 Antibody (6K323) can be used in ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $68 | 7-10 days | |
100 μL | $199 | 7-10 days |
Description | Anti-IL-19 Antibody (6K323) is a Mouse antibody targeting IL-19. Anti-IL-19 Antibody (6K323) can be used in ELISA(Cap). |
Alias | ZMDA1, NG.1, MDA1, Interleukin-19, interleukin 19, IL-10C |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 6K323 |
Reactivity | Human |
Application | ELISA(Cap) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL19 / Interleukin-19 (rh IL19 / Interleukin-19; AAF06663.1Met1-Ala177). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the epithelial barrier with dextran sodium sulfate leads to increased IL-19 expression. Attenuated colitis in IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. Microbial-driven expression of IL-19 by intestinal macrophages may contribute to the pathogenesis of inflammatory bowel disease. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human IL19 / Interleukin-19 Protein |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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