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Clazakizumab

Catalog No. T76675 Copy Product Info
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Clazakizumab is a humanized monoclonal antibody targeting human interleukin -6(IL-6) with high affinity. By directly binding IL-6 ligand, it blocks its interaction with IL-6 receptor (IL-6α) and signal co-receptor gp130, thus inhibiting the activation of downstream JAK/STAT signaling pathway and weakening the inflammatory response. Clazakizumab can be used in the study of psoriasis arthritis and antibody-mediated organ transplant rejection.

Clazakizumab

Copy Product Info
🥰Excellent
Catalog No. T76675

Clazakizumab is a humanized monoclonal antibody targeting human interleukin -6(IL-6) with high affinity. By directly binding IL-6 ligand, it blocks its interaction with IL-6 receptor (IL-6α) and signal co-receptor gp130, thus inhibiting the activation of downstream JAK/STAT signaling pathway and weakening the inflammatory response. Clazakizumab can be used in the study of psoriasis arthritis and antibody-mediated organ transplant rejection.

Clazakizumab
Cas No. 1236278-28-6
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$415-In Stock
5 mg$1,250-In Stock
10 mg$1,990-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.7% (SDS-PAGE); 98.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Clazakizumab is a humanized monoclonal antibody targeting human interleukin -6(IL-6) with high affinity. By directly binding IL-6 ligand, it blocks its interaction with IL-6 receptor (IL-6α) and signal co-receptor gp130, thus inhibiting the activation of downstream JAK/STAT signaling pathway and weakening the inflammatory response. Clazakizumab can be used in the study of psoriasis arthritis and antibody-mediated organ transplant rejection.
Targets&IC50
IL-6:< 10 pM(Kd)
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetIL-6
Chemical Properties
Cas No.1236278-28-6
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice/Shipping at ambient temperature.

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