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CaMKI(299-320)

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Catalog No. TP2683Cas No. 205598-38-5
Alias Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain

CaMKI (299-320) is a peptide representing residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). This segment, functioning as a protein kinase, exhibits a strong interaction with Ca 2+ -CAM (K d ≤1 nM), enabling it to phosphorylate specific substrate proteins and regulate their activity. It encompasses both the CAM-binding domain and the self-inhibition domain. CaMKI (299-320) is applicable for researching cellular physiological processes such as proliferation, differentiation, and apoptosis .

CaMKI(299-320)

CaMKI(299-320)

😃Good
Catalog No. TP2683Alias Calmodulin-Dependent Protein Kinase I (299-320) Binding DomainCas No. 205598-38-5
CaMKI (299-320) is a peptide representing residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). This segment, functioning as a protein kinase, exhibits a strong interaction with Ca 2+ -CAM (K d ≤1 nM), enabling it to phosphorylate specific substrate proteins and regulate their activity. It encompasses both the CAM-binding domain and the self-inhibition domain. CaMKI (299-320) is applicable for researching cellular physiological processes such as proliferation, differentiation, and apoptosis .
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Product Introduction

Bioactivity
Description
CaMKI (299-320) is a peptide representing residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). This segment, functioning as a protein kinase, exhibits a strong interaction with Ca 2+ -CAM (K d ≤1 nM), enabling it to phosphorylate specific substrate proteins and regulate their activity. It encompasses both the CAM-binding domain and the self-inhibition domain. CaMKI (299-320) is applicable for researching cellular physiological processes such as proliferation, differentiation, and apoptosis .
SynonymsCalmodulin-Dependent Protein Kinase I (299-320) Binding Domain
Chemical Properties
Molecular Weight2599.07
FormulaC116H192N38O28S
Cas No.205598-38-5
SmilesC([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CCSC)=O)=O)CCCNC(=N)N)=O)C(C)C)=O)C(C)C)=O)C)=O)[C@@H](C)O)=O)C)=O)CC(N)=O)=O)=O)C)=O)CCC(N)=O)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@H](C)N)=O)=O)CO)=O)CCCCN)=O)C=3C=4C(NC3)=CC=CC4
SequenceAla-Lys-Ser-Lys-Trp-Lys-Gln-Ala-Phe-Asn-Ala-Thr-Ala-Val-Val-Arg-His-Met-Arg-Lys-Leu-Gln
Sequence ShortAKSKWKQAFNATAVVRHMRKLQ
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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