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Anti-AGTR1 Antibody (1C446) is an antibody targeting AGTR1. Anti-AGTR1 Antibody (1C446) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human |
Ig Type | Rabbit IgG |
Clone | 1C446 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: Hela whole cell lysate, Raji whole cell lysate, MCF-7 whole cell lysate -All lanes: AGTR1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 42 kDa -Observed band size: 42 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human AGTR1 |
Antigen Species | Human |
Gene ID | 185 |
Uniprot ID | |
Biology Area | Cancer, Cardiovascular, Metabolism |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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