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L-Tartaric acid

Name: L-Tartaric acid
Brand: TargetMol
SKU: T5059
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5059Cas No. 87-69-4

Alias L(+)-Tartaric acid, (2R,3R)-(+)-Tartaric acid

L-Tartaric acid ((2R,3R)-(+)-Tartaric acid) occurs naturally in many plants, particularly grapes and tamarinds, and is one of the main acids found in wine. It is used as an antioxidant. Salts of tartaric acid are known as tartrates. L-Tartaric acid is a muscle toxin, which works by inhibiting the production of malic acid, and in high doses causes paralysis and death.

L-Tartaric acid

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Purity: 99.38%

Catalog No. T5059Alias L(+)-Tartaric acid, (2R,3R)-(+)-Tartaric acidCas No. 87-69-4

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$30	In Stock	In Stock
500 mg	$42	In Stock	In Stock
1 g	$58	In Stock	In Stock
2 g	$82	-	In Stock
5 g	$133	-	In Stock
10 g	$195	-	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.38%

Appearance:Solid

Color:White

Resource Download

COA HPLC LCMS HNMR

Product Introduction

L-Tartaric acid AI Summary

L-Tartaric acid exhibits a range of bioactivities. It demonstrates inhibitory potency against AmpC Beta-Lactamase at 631.0 nM in a detergent-based assay, while it inhibits the JMJD2A-Tudor Domain at 100000.0 nM. It acts as a delayed death inhibitor of the malarial parasite plastid with a potency of 9285.0 nM over 96 hours. Additionally, L-Tartaric acid induces DNA re-replication in MCF 10a normal breast cells with a potency of 4.6 nM and in SW480 colon adenocarcinoma cells with a potency of 32642.7 nM. Regarding its antiviral properties, L-Tartaric acid exhibits activity against SARS-CoV-2 by inhibiting cytotoxicity of Caco-2 cells by 45.3% at a concentration of 10 μM after 48 hours, as determined by high content imaging. It inhibits the SARS-CoV-2 3CL-Pro protease by 12.48% at a concentration of 20 μM based on FRET from a peptide substrate. However, its inhibitory rate against SARS-CoV-2 induced cytotoxicity in VERO-6 cells is quite low at 0.08% at 10 μM after 48 hours. The IC50 value for its activity against SARS-CoV-2 induced cytotoxicity in VERO-6 cells is reported to be greater than 20000.0 nM, indicating limited efficacy in this assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	L-Tartaric acid ((2R,3R)-(+)-Tartaric acid) occurs naturally in many plants, particularly grapes and tamarinds, and is one of the main acids found in wine. It is used as an antioxidant. Salts of tartaric acid are known as tartrates. L-Tartaric acid is a muscle toxin, which works by inhibiting the production of malic acid, and in high doses causes paralysis and death.
Synonyms	L(+)-Tartaric acid, (2R,3R)-(+)-Tartaric acid

Chemical Properties

Molecular Weight	150.09
Formula	C₄H₆O₆
Cas No.	87-69-4
Smiles	O[C@H]([C@@H](O)C(O)=O)C(O)=O
Relative Density.	Ca. 1.76 g/cm3.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1665.67 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.33 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.6627 mL	33.3133 mL	66.6267 mL	333.1335 mL
5 mM	1.3325 mL	6.6627 mL	13.3253 mL	66.6267 mL
10 mM	0.6663 mL	3.3313 mL	6.6627 mL	33.3133 mL
20 mM	0.3331 mL	1.6657 mL	3.3313 mL	16.6567 mL
50 mM	0.1333 mL	0.6663 mL	1.3325 mL	6.6627 mL
100 mM	0.0666 mL	0.3331 mL	0.6663 mL	3.3313 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc