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BI-2536 monohydrate

Name: BI-2536 monohydrate
Brand: TargetMol
SKU: T202280
Rating: 4.5 (1 reviews)

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Catalog No. T202280Cas No. 876126-71-5

Alias BI-2536, BI2536, BI 2536

BI-2563 is a small molecule compound with potential antitumor properties. It binds to Polo-like kinase 1 (Plk1) and inhibits its activity, resulting in mitotic arrest, interruption of cell division, and apoptosis in susceptible tumor cell populations. Plk1 is a serine/threonine-protein kinase that serves as a key regulator of several critical processes essential for mitosis and cytokinesis.

BI-2536 monohydrate

😃Good

Catalog No. T202280Alias BI-2536, BI2536, BI 2536Cas No. 876126-71-5

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	10-14 weeks
50 mg	Inquiry	10-14 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	BI-2563 is a small molecule compound with potential antitumor properties. It binds to Polo-like kinase 1 (Plk1) and inhibits its activity, resulting in mitotic arrest, interruption of cell division, and apoptosis in susceptible tumor cell populations. Plk1 is a serine/threonine-protein kinase that serves as a key regulator of several critical processes essential for mitosis and cytokinesis.
Synonyms	BI-2536, BI2536, BI 2536

Chemical Properties

Molecular Weight	539.67
Formula	C₂₈H₄₁N₇O₄
Cas No.	876126-71-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc