Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Autotaxin-IN-6 (compound 23) is a potent inhibitor of autotaxin (ATX), exhibiting an IC50 of 30 nM, and is capable of attenuating cell migration with potential applications in anticancer research [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Autotaxin-IN-6 (compound 23) is a potent inhibitor of autotaxin (ATX), exhibiting an IC50 of 30 nM, and is capable of attenuating cell migration with potential applications in anticancer research [1]. |
Targets&IC50 | ATX:30 nM |
In vitro | Autotaxin-IN-6 (compound 23) effectively inhibits ATX-induced activity in HeLa cells, leading to a marked reduction in LPA1 internalization by about 75% [1]. Furthermore, it impedes LPA1 activation and disrupts downstream Gαi- and PI3K-dependent signaling pathways [1]. |
Molecular Weight | 595.62 |
Formula | C35H54BNO6 |
CAS No. | 2800898-98-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Autotaxin-IN-6 2800898-98-8 inhibitor inhibit