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(D-His(Bzl)6)-LHRH (1-7) (free acid)
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Catalog No. TP2755Cas No. 1926163-27-0
(D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide derived from luteinizing hormone-releasing hormone (LHRH). It achieves enhanced stability and biological activity through the introduction of non-natural amino acid residues at specific positions within the LHRH molecule. This modification extends the drug's half-life in the body, reduces its rate of rapid metabolism and clearance, and subsequently increases its efficacy in inhibiting cell proliferation.
(D-His(Bzl)6)-LHRH (1-7) (free acid)
😃Good
Catalog No. TP2755Cas No. 1926163-27-0
(D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide derived from luteinizing hormone-releasing hormone (LHRH). It achieves enhanced stability and biological activity through the introduction of non-natural amino acid residues at specific positions within the LHRH molecule. This modification extends the drug's half-life in the body, reduces its rate of rapid metabolism and clearance, and subsequently increases its efficacy in inhibiting cell proliferation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Chemical Properties
| Description | (D-His(Bzl)6)-LHRH (1-7) free acid is a synthetic peptide derived from luteinizing hormone-releasing hormone (LHRH). It achieves enhanced stability and biological activity through the introduction of non-natural amino acid residues at specific positions within the LHRH molecule. This modification extends the drug's half-life in the body, reduces its rate of rapid metabolism and clearance, and subsequently increases its efficacy in inhibiting cell proliferation. |
| Molecular Weight | 1043.13 |
| Formula | C53H62N12O11 |
| Cas No. | 1926163-27-0 |
| Sequence | {Pyr}-His-Trp-Ser-Tyr-{d-His(Bzl)}-Leu |
| Sequence Short | {Pyr}-HWSY-{d-His(Bzl)}-L |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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