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Anti-MADCAM1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting MADCAM1. Anti-MADCAM1 Monoclonal Antibody-Biotin can be used in ELISA, FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $1,330 | 12 days | |
50 μg | $1,596 | 12 days | |
100 μg | $2,234 | 12 days |
Description | Antibody Type: Rabbit Monoclonal Application: ELISA, FCM Reactivity: Human |
Alias | Mucosal addressin cell adhesion molecule 1 |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of MADCAM1 overexpressed 381F cells with TMAZ-0169B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FCM |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MADCAM1 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in PBS. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding |
Conjucates | Biotin |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | MADCAM1 |
Antigen Species | Human |
Gene ID | 8174 |
Uniprot ID | |
Biology Area | Drug Target |
Molecular Weight | 150 kDa |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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