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Anti-DNase I Antibody (4N202)
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Catalog No. TMAY-02628
Anti-DNase I Antibody (4N202) is a Rabbit antibody targeting DNase I. Anti-DNase I Antibody (4N202) can be used in ELISA.
Anti-DNase I Antibody (4N202)
Anti-DNase I Antibody (4N202)
😃Good
Catalog No. TMAY-02628
Anti-DNase I Antibody (4N202) is a Rabbit antibody targeting DNase I. Anti-DNase I Antibody (4N202) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DNase I Antibody (4N202) is a Rabbit antibody targeting DNase I. Anti-DNase I Antibody (4N202) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4N202 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human DNase1 / Deoxyribonuclease I / DNL1 (rh DNase1 / Deoxyribonuclease I / DNL1; TMPY-03855; P24855; Met1-Lys282). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. DNaseI binds to the cytoskeletal protein actin. It binds actin monomers with very high (sub-nanomolar) affinity and actin polymers with lower affinity. Mutations in DNase1 gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. DNase1 is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human DNase1 / Deoxyribonuclease I / DNL1 Protein (TMPY-03855) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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