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Licoflavone C

Name: Licoflavone C
Brand: TargetMol
SKU: TN1861
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1861Cas No. 72357-31-4

Alias 4',5,7-Trihydroxy-8-prenylflavone

Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a protective effect against DAU or MMC-induced chromosome damage in cultured human peripheral lymphocytes. Licoflavone C can be used to study fungal infections.

Licoflavone C

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Purity: 99.71%

Catalog No. TN1861Alias 4',5,7-Trihydroxy-8-prenylflavoneCas No. 72357-31-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$179	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.71%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a protective effect against DAU or MMC-induced chromosome damage in cultured human peripheral lymphocytes. Licoflavone C can be used to study fungal infections.
In vitro	After using two non-toxic Licoflavone C concentrations (0.1 microM and 1.0 microM). The MN frequencies induced by 0.025 microg/ml or 0.05 microg/ml DAU were significantly lowered by 45.4% or 46.6% and 41.8% or 44.8% at Licoflavone C 0.1 and 1.0 microM, respectively[1].
Synonyms	4',5,7-Trihydroxy-8-prenylflavone

Chemical Properties

Molecular Weight	338.35
Formula	C₂₀H₁₈O₅
Cas No.	72357-31-4
Smiles	CC(C)=CCc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
Relative Density.	1.351 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (295.55 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9555 mL	14.7776 mL	29.5552 mL	147.7760 mL
5 mM	0.5911 mL	2.9555 mL	5.9110 mL	29.5552 mL
10 mM	0.2956 mL	1.4778 mL	2.9555 mL	14.7776 mL
20 mM	0.1478 mL	0.7389 mL	1.4778 mL	7.3888 mL
50 mM	0.0591 mL	0.2956 mL	0.5911 mL	2.9555 mL
100 mM	0.0296 mL	0.1478 mL	0.2956 mL	1.4778 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc