Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CaV1.3 antagonist-1 is a cyclopentyl derivative with the potential for the research of Parkinson's disease. CaV1.3 antagonist-1 inhibits Ca V 1.3 LTCC over 600-fold more effectively than Ca V 1.2 LTCC. CaV1.3 antagonist-1 is a potent and highly selective antagonist of Ca V 1.3 L-type calcium channel (LTCC) with an IC50 value of 1.7 μM [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 977.00 | |
50 mg | 6-8 weeks | $ 1,270.00 | |
100 mg | 6-8 weeks | $ 1,990.00 |
Description | CaV1.3 antagonist-1 is a cyclopentyl derivative with the potential for the research of Parkinson's disease. CaV1.3 antagonist-1 inhibits Ca V 1.3 LTCC over 600-fold more effectively than Ca V 1.2 LTCC. CaV1.3 antagonist-1 is a potent and highly selective antagonist of Ca V 1.3 L-type calcium channel (LTCC) with an IC50 value of 1.7 μM [1]. |
In vitro | CaV1.3 antagonist-1 (Compound 8; 5 μM) demonstrates inhibition of Ca V 1.3 and Ca V 1.2 channel currents in HEK293 cells at 31.2% and 4.4%, respectively. These findings are consistent with the outcomes of the FLIPR assay [1]. |
Molecular Weight | 334.8 |
Formula | C17H19ClN2O3 |
CAS No. | 1391385-57-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CaV1.3 antagonist-1 1391385-57-1 inhibitor inhibit