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Anti-TSC22D1 Antibody (9D388)

😃Good
Catalog No. TMAY-02410
Alias TSC22 domain family, member 1, TSC22, TGFB1I4, Ptg-2

Anti-TSC22D1 Antibody (9D388) is a Rabbit antibody targeting TSC22D1. Anti-TSC22D1 Antibody (9D388) can be used in ICC/IF.

Anti-TSC22D1 Antibody (9D388)

Anti-TSC22D1 Antibody (9D388)

😃Good
Catalog No. TMAY-02410Alias TSC22 domain family, member 1, TSC22, TGFB1I4, Ptg-2
Anti-TSC22D1 Antibody (9D388) is a Rabbit antibody targeting TSC22D1. Anti-TSC22D1 Antibody (9D388) can be used in ICC/IF.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TSC22D1 Antibody (9D388) is a Rabbit antibody targeting TSC22D1. Anti-TSC22D1 Antibody (9D388) can be used in ICC/IF.
AliasTSC22 domain family, member 1, TSC22, TGFB1I4, Ptg-2
Ig Type
Monoclonal Rabbit IgG
Clone
9D388
Reactivity
Human
Verified Activity
Immunofluorescence staining of Human TSC22D1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TSC22D1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue). Positive staining was localized to nucleus and cytoplasm.
Application
ICC/IF
Recommended Dose
ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TSC22D1 (rh TSC22D1; TMPY-02400; Q15714-2; Met1-Ala144).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor that negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human TSC22D1 Protein (TMPY-02400)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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