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Anti-SUMO1 Antibody (2Z121) is a Rabbit antibody targeting SUMO1. Anti-SUMO1 Antibody (2Z121) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-SUMO1 Antibody (2Z121) is a Rabbit antibody targeting SUMO1. Anti-SUMO1 Antibody (2Z121) can be used in ELISA. |
Alias | UBL1, SMT3H3, SMT3C, SMT3, small ubiquitin-like modifier 1, SENP2, PIC1, OFC10, GMP1, DAP1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2Z121 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SUMO1 / SUMO-1 (rh SUMO1 / SUMO-1; TMPY-02391; AAH66306.1; Ser2-Val101). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific proteases (SENPs). Small ubiquitin-like modifier 1 (SUMO1) is a member of the superfamily of ubiquitin-like proteins. Despite its structural similarity with ubiquitin, SUMO1 does not seem to play any role in protein degradation. SUMO1 plays an important role in modulation of NOX activity required for ROS generation. SUMO1 haploinsufficiency results in cleft lip and palate in animal models. SUMO1 gene variation in human non-syndromic cleft lip with or without cleft palate (NSCLP) development. SUMO-1 may be useful as a novel target for therapy in oral squamous cell carcinoma (SCC) as well as a clinical indicator for tumor recurrence together with Mdm2. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human SUMO1 / SUMO-1 protein (TMPY-02391) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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