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Humantenine

Name: Humantenine
Brand: TargetMol
SKU: TN1747
Rating: 4.5 (1 reviews)

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Catalog No. TN1747Cas No. 82375-29-9

Humantenine, a naturally occurring indole alkaloid derived from *Gelsemium elegans*, HCT116 cell injury induced by humantenine was associated with the abnormal mRNA expression of m6A regulators

Humantenine

😃Good

Catalog No. TN1747Cas No. 82375-29-9

Humantenine, a naturally occurring indole alkaloid derived from *Gelsemium elegans*, HCT116 cell injury induced by humantenine was associated with the abnormal mRNA expression of m6A regulators

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5 mg	$750	Backorder

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Description

Humantenine, a naturally occurring indole alkaloid derived from *Gelsemium elegans*, HCT116 cell injury induced by humantenine was associated with the abnormal mRNA expression of m6A regulators

In vitro

Nine new alkaloids of the koumine (1-4), Humantenine (5-7), and yohimbane (8, 9) types as well as 12 known analogues were isolated from the leaves and vine stems of Gelsemium elegans. Compound 1 is the first N-4-demethyl alkaloid of the koumine type, compound 7 is the first nor-Humantenine alkaloid, and compounds 8 and 9 are the first N-1-oxide and the first seco-E-ring alkaloids, respectively, of the yohimbane type.

Chemical Properties

Molecular Weight	354.44
Formula	C₂₁H₂₆N₂O₃
Cas No.	82375-29-9
Smiles	O=C1[C@@]2(C=3C(N1OC)=CC=CC3)[C@]4(C[C@@]\5([C@@]([C@](C2)(N(C)C/C5=C\C)[H])(CO4)[H])[H])[H]
Relative Density.	1.27 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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Keywords

Humantenine