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BC 11-38

Name: BC 11-38
Brand: TargetMol
SKU: T21865
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21865Cas No. 686770-80-9

BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).

BC 11-38

🥰Excellent

Purity: 99.28%

Catalog No. T21865Cas No. 686770-80-9

BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).

Pack Size	Price	Availability
1 mg	$30	In Stock
5 mg	$64	In Stock
10 mg	$98	In Stock
25 mg	$213	In Stock
50 mg	$347	In Stock
100 mg	$555	In Stock
200 mg	$787	In Stock
1 mL x 10 mM (in DMSO)	$74	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.28%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).
Targets&IC50	PDE10:>100 μM, PDE11:0.28 μM
In vitro	BC 11-38 ignificantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells [1].

Chemical Properties

Molecular Weight	304.43
Formula	C₁₅H₁₆N₂OS₂
Cas No.	686770-80-9
Smiles	CCCSc1nc2CCSc2c(=O)n1-c1ccccc1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (164.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2848 mL	16.4241 mL	32.8483 mL	164.2414 mL
5 mM	0.6570 mL	3.2848 mL	6.5697 mL	32.8483 mL
10 mM	0.3285 mL	1.6424 mL	3.2848 mL	16.4241 mL
20 mM	0.1642 mL	0.8212 mL	1.6424 mL	8.2121 mL
50 mM	0.0657 mL	0.3285 mL	0.6570 mL	3.2848 mL
100 mM	0.0328 mL	0.1642 mL	0.3285 mL	1.6424 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc