Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction with an IC50 of 0.8 nM, leading to an enhanced LDL uptake in HepG2 cells [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,670.00 | |
50 mg | 8-10 weeks | $ 2,180.00 | |
100 mg | 8-10 weeks | $ 2,800.00 |
Description | Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction with an IC50 of 0.8 nM, leading to an enhanced LDL uptake in HepG2 cells [1]. |
Molecular Weight | 583.55 |
Formula | C29H38IN5 |
CAS No. | 2743448-32-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dim16 2743448-32-8 inhibitor inhibit