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Anti-Gremlin-1 Antibody (3L967)
(Synonyms: GREM1) Copy Product Info
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Synonyms: GREM1
Catalog No. TMAH-00512 Copy Product Info
🥰Excellent
Anti-Gremlin-1 Antibody (3L967) is an antibody targeting Gremlin-1. Anti-Gremlin-1 Antibody (3L967) can be used in ELISA,IHC.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Gremlin-1 Antibody (3L967) is an antibody targeting Gremlin-1. Anti-Gremlin-1 Antibody (3L967) can be used in ELISA,IHC. |
| Synonyms | GREM1 |
| Ig Type | hIgG1 |
| Clone | 3L967 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Highly expressed in small intestine, fetal brain and colon. Expression is restricted to intestinal subepithelial myofibroblasts (ISEMFs) at the crypt base. In subjects with HMPS1, by contrast, GREM1 is expressed, not only in basal ISEMFs, but also at very |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GREM1 Protein |
| Antigen Species | Human |
| Gene Name | GREM1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal transduction, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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