Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 41.00 | |
100 mg | In stock | $ 66.00 | |
200 mg | In stock | $ 94.00 | |
500 mg | In stock | $ 158.00 |
Description | HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. |
In vitro | HIV-1 integrase inhibitor 8 were tested against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn2+ as the cationic cofactor by gel assay, IC50=275μM and 231μM, respectively. HIV-1 integrase inhibitor 8 were retested using Mg2+ and the IC50 of against strand-transfer (ST) activities was 200μM. HIV-1 integrase inhibitor 8 inhibits MCV topoisomerase and DNA religation with IC50 of 500 µM and 200 µM, respectively. HIV-1 integrase inhibitor 8 induces cell cytotoxicity with LD50 of 20 μM in HeLa cells[1]. |
Molecular Weight | 308.41 |
Formula | C21H24O2 |
CAS No. | 1568-80-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 112.5 mg/mL (364.8 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HIV-1 integrase inhibitor 8 1568-80-5 Microbiology/Virology Proteases/Proteasome HIV Protease inhibitor inhibit