Decanoyl-RVKR-CMK TFA

Name: Decanoyl-RVKR-CMK TFA
Brand: TargetMol
SKU: T39526
Rating: 4.5 (1 reviews)

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Catalog No. T39526Cas No. 2098497-25-5

Alias DecRVKRcmk TFA, Decanoyl-RVKR-CMK TFA

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.

Decanoyl-RVKR-CMK TFA

😃Good

Catalog No. T39526Alias DecRVKRcmk TFA, Decanoyl-RVKR-CMK TFACas No. 2098497-25-5

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$537	Inquiry	Inquiry
10 mg	$872	Inquiry	Inquiry
50 mg	Inquiry	Inquiry	Inquiry
100 mg	Inquiry	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication.
In vitro	Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively inhibits HIV-2 ROD replication by impeding the processing of envelope glycoprotein precursors in Jurkat lymphocyte cells[1] and obstructs the regulated secretion of VGF[2]. In a cell viability assay with HeLaCD4 cells infected with recombinant vaccinia viruses at 5 PFU/mL MOI, 35 μM concentration reduced ex vivo HIV-1 and HIV-2 replication rates by 70-80% over 7 days.
Synonyms	DecRVKRcmk TFA, Decanoyl-RVKR-CMK TFA

Chemical Properties

Molecular Weight	858.45
Formula	C₃₆H₆₇ClF₃N₁₁O₇
Cas No.	2098497-25-5
Smiles	OC(=O)C(F)(F)F.CCCCCCCCCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CCl
Relative Density.	no data available
Sequence	decanoyl-Arg-Val-Lys-Arg-CH2Cl.TFA
Sequence Short	RVKR

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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