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Avenanthramide-C methyl ester

Name: Avenanthramide-C methyl ester
Brand: TargetMol
SKU: T36198
Rating: 4.5 (1 reviews)

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Catalog No. T36198Cas No. 955382-52-2

Avenanthramide-C methyl ester inhibits NF-κB activation by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM), thereby dose-dependently inhibiting the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.

Avenanthramide-C methyl ester

😃Good

Catalog No. T36198Cas No. 955382-52-2

Pack Size	Price	Availability
500 μg	$138	35 days
1 mg	$253	35 days
5 mg	$1,050	35 days
10 mg	$1,830	35 days

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	329.3
Formula	C₁₇H₁₅NO₆
Cas No.	955382-52-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL (1.52 mM), Sonication is recommended.

DMSO: 20 mg/mL (60.73 mM), Sonication is recommended.

DMF: 20 mg/mL (60.73 mM), Sonication is recommended.

Ethanol: 10 mg/mL (30.37 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6073 mL	3.0367 mL	6.0735 mL	30.3674 mL
10 mM	0.3037 mL	1.5184 mL	3.0367 mL	15.1837 mL
20 mM	0.1518 mL	0.7592 mL	1.5184 mL	7.5919 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
50 mM	0.0607 mL	0.3037 mL	0.6073 mL	3.0367 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc