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Anti-TEM7 Antibody (3I752)

😃Good
Catalog No. TMAY-02032
Alias TEM7, TEM3, plexin domain containing 1

Anti-TEM7 Antibody (3I752) is a Mouse antibody targeting TEM7. Anti-TEM7 Antibody (3I752) can be used in ELISA(Cap).

Anti-TEM7 Antibody (3I752)

Anti-TEM7 Antibody (3I752)

😃Good
Catalog No. TMAY-02032Alias TEM7, TEM3, plexin domain containing 1
Anti-TEM7 Antibody (3I752) is a Mouse antibody targeting TEM7. Anti-TEM7 Antibody (3I752) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TEM7 Antibody (3I752) is a Mouse antibody targeting TEM7. Anti-TEM7 Antibody (3I752) can be used in ELISA(Cap).
AliasTEM7, TEM3, plexin domain containing 1
Ig Type
Monoclonal Mouse IgG1
Clone
3I752
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; TMPY-02100; AAH36059.1; Met1-Thr426). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPlexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human TEM7 / PLXDC1 Protein (TMPY-02100)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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