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Anti-ADAR Antibody (1G868) is an antibody targeting ADAR. Anti-ADAR Antibody (1G868) can be used in ELISA, IHC.
Description | Anti-ADAR Antibody (1G868) is an antibody targeting ADAR. Anti-ADAR Antibody (1G868) can be used in ELISA, IHC. |
Ig Type | Rabbit IgG |
Clone | 1G868 |
Reactivity | Human |
Verified Activity | IHC image of TMAH-00028 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
Application | ELISA, IHC |
Recommended Dose | IHC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 5]: Cytoplasm. Nucleus. Nucleus, nucleolus. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA produ... |
Conjucates | Unconjugated |
Immunogen | A synthesized peptide derived from human ADAR1 |
Antigen Species | Human |
Gene ID | 103 |
Uniprot ID | |
Biology Area | Epigenetics and Nuclear Signaling, Microbiology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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