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Azido-FTY720

Name: Azido-FTY720
Brand: TargetMol
SKU: T37548
Rating: 4.5 (1 reviews)

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Catalog No. T37548Cas No. 881914-35-8

Alias Azido-FTY 720, Azido FTY720, Azido FTY 720

Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720 featuring an azido group suitable for click chemistry reactions. FTY720 is an orally available S1P analogue and S1P1R modulator capable of crossing the blood-brain barrier (BBB), reducing neuroinflammation, and is indicated for multiple sclerosis (MS).

Azido-FTY720

😃Good

Catalog No. T37548Alias Azido-FTY 720, Azido FTY720, Azido FTY 720Cas No. 881914-35-8

Pack Size	Price	USA Warehouse	Global Warehouse
100 μg	$120	35 days	35 days
500 μg	$519	35 days	35 days
1 mg	$920	35 days	35 days
5 mg	$3,920	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720 featuring an azido group suitable for click chemistry reactions. FTY720 is an orally available S1P analogue and S1P1R modulator capable of crossing the blood-brain barrier (BBB), reducing neuroinflammation, and is indicated for multiple sclerosis (MS).
Synonyms	Azido-FTY 720, Azido FTY720, Azido FTY 720

Chemical Properties

Molecular Weight	348.49
Formula	C₁₉H₃₂N₄O₂
Cas No.	881914-35-8
Smiles	[N-]=[N+]=NC1=CC(=CC=C1CCCCCCCC)CCC(N)(CO)CO
Color	Yellow
Appearance	Liquid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 10.00 mg/mL (28.70 mM), Sonication is recommended.

DMF: 10.00 mg/mL (28.70 mM), Sonication is recommended.

DMSO: 10.00 mg/mL (28.70 mM), Sonication is recommended.

Ethanol:PBS (pH 7.2) (1:1): < 1 mg/mL (insoluble), Sonication is recommended.

Solution Preparation Table

Ethanol/DMF/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8695 mL	14.3476 mL	28.6952 mL	143.4761 mL
5 mM	0.5739 mL	2.8695 mL	5.7390 mL	28.6952 mL
10 mM	0.2870 mL	1.4348 mL	2.8695 mL	14.3476 mL
20 mM	0.1435 mL	0.7174 mL	1.4348 mL	7.1738 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc