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Azido-FTY720

Name: Azido-FTY720
Brand: TargetMol
SKU: T37548
Rating: 4.5 (1 reviews)

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Catalog No. T37548Cas No. 881914-35-8

Alias Azido-FTY 720, Azido FTY720, Azido FTY 720

Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720 featuring an azido group suitable for click chemistry reactions. FTY720 is an orally available S1P analogue and S1P1R modulator capable of crossing the blood-brain barrier (BBB), reducing neuroinflammation, and is indicated for multiple sclerosis (MS).

Azido-FTY720

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Catalog No. T37548Alias Azido-FTY 720, Azido FTY720, Azido FTY 720Cas No. 881914-35-8

Pack Size	Price	USA Warehouse	Global Warehouse
100 μg	$120	35 days	35 days
500 μg	$519	35 days	35 days
1 mg	$920	35 days	35 days
5 mg	$3,920	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Liquid

Color:Yellow

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COA

Product Introduction

Bioactivity

Description	Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720 featuring an azido group suitable for click chemistry reactions. FTY720 is an orally available S1P analogue and S1P1R modulator capable of crossing the blood-brain barrier (BBB), reducing neuroinflammation, and is indicated for multiple sclerosis (MS).
Synonyms	Azido-FTY 720, Azido FTY720, Azido FTY 720

Chemical Properties

Molecular Weight	348.49
Formula	C₁₉H₃₂N₄O₂
Cas No.	881914-35-8
Smiles	[N-]=[N+]=NC1=CC(=CC=C1CCCCCCCC)CCC(N)(CO)CO

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 10 mg/mL (28.7 mM), Sonication is recommended.

DMF: 10 mg/mL (28.7 mM), Sonication is recommended.

DMSO: 10 mg/mL (28.7 mM), Sonication is recommended.

Ethanol:PBS (pH 7.2) (1:1): < 1 mg/mL (insoluble), Sonication is recommended.

Solution Preparation Table

Ethanol/DMF/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8695 mL	14.3476 mL	28.6952 mL	143.4761 mL
5 mM	0.5739 mL	2.8695 mL	5.7390 mL	28.6952 mL
10 mM	0.2870 mL	1.4348 mL	2.8695 mL	14.3476 mL
20 mM	0.1435 mL	0.7174 mL	1.4348 mL	7.1738 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc