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Reltecimod TFA

🥰Excellent
Catalog No. T78107
Alias Reltecimod TFA, AB-103 TFA, AB103 TFA

Reltecimod TFA (AB-103 TFA) is a CD28 (T-lymphocyte receptor) mimetic that acts as a CD28 antagonist, inhibiting the stimulation of t-cells by a range of bacterial pathogens thereby attenuating acute inflammation for the treatment of necrotizing soft tissue infections (NSTI).

Reltecimod TFA
Other Forms of Reltecimod TFA:

Reltecimod TFA

🥰Excellent
Purity: 99.78%
Catalog No. T78107Alias Reltecimod TFA, AB-103 TFA, AB103 TFA
Reltecimod TFA (AB-103 TFA) is a CD28 (T-lymphocyte receptor) mimetic that acts as a CD28 antagonist, inhibiting the stimulation of t-cells by a range of bacterial pathogens thereby attenuating acute inflammation for the treatment of necrotizing soft tissue infections (NSTI).
Pack SizePriceAvailabilityQuantity
5 mg$35In Stock
10 mg$54In Stock
25 mg$113In Stock
50 mg$183In Stock
100 mg$275In Stock
200 mg$412In Stock
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Purity:99.78%
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COA HPLC MS
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Reltecimod TFA (AB-103 TFA) is a CD28 (T-lymphocyte receptor) mimetic that acts as a CD28 antagonist, inhibiting the stimulation of t-cells by a range of bacterial pathogens thereby attenuating acute inflammation for the treatment of necrotizing soft tissue infections (NSTI).
In vivo
Reltecimod TFA, administered intravenously at dosages ranging from 1.25 to 5 mg/kg, has been shown to enhance survival rates in mice infected with various bacteria [1].
AliasReltecimod TFA, AB-103 TFA, AB103 TFA
Chemical Properties
Molecular Weight1151.21
FormulaC48H73F3N10O17S
Smiles[H]N[C@@H](C)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCSC)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)C(C)C)=O)CC(C)C)=O)=O)=O)CO)=O.OC(C(F)(F)F)=O
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMSO: 80.00 mg/mL (69.49 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8687 mL4.3433 mL8.6865 mL43.4326 mL
5 mM0.1737 mL0.8687 mL1.7373 mL8.6865 mL
10 mM0.0869 mL0.4343 mL0.8687 mL4.3433 mL
20 mM0.0434 mL0.2172 mL0.4343 mL2.1716 mL
50 mM0.0174 mL0.0869 mL0.1737 mL0.8687 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
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%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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