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Clerosterol

Name: Clerosterol
Brand: TargetMol
SKU: TN3681
Rating: 4.5 (1 reviews)

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Catalog No. TN3681Cas No. 2364-23-0

Alias (-)-Clerosterol

Clerosterol ((-)-Clerosterol) is a small molecule compound derived from Roasted bupleuri in vinegar that inhibits Pgp overexpression. Clerosterol shows cytotoxicity to human melanoma cells and can be used to study the loss of mitochondrial membrane potential.

Clerosterol

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Catalog No. TN3681Alias (-)-ClerosterolCas No. 2364-23-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	Inquiry	Backorder	Backorder
5 mg	Inquiry	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Clerosterol ((-)-Clerosterol) is a small molecule compound derived from Roasted bupleuri in vinegar that inhibits Pgp overexpression. Clerosterol shows cytotoxicity to human melanoma cells and can be used to study the loss of mitochondrial membrane potential.
In vitro	Clerosterol is a natural compound with certain antioxidant and anticancer activities[3].
Synonyms	(-)-Clerosterol

Chemical Properties

Molecular Weight	412.69
Formula	C₂₉H₄₈O
Cas No.	2364-23-0
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@@H](C(C)=C)CC)C)[H])[H]
Relative Density.	0.98g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc