Powder: -20°C for 3 years | In solvent: -80°C for 1 year
αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 values of 380 nM (ανβ3), 280 nM (ανβ5), 230 nM (ανβ6), and 87 nM (ανβ8) as determined by the SPRA assay [1].
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Description | αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 values of 380 nM (ανβ3), 280 nM (ανβ5), 230 nM (ανβ6), and 87 nM (ανβ8) as determined by the SPRA assay [1]. |
Molecular Weight | 506.64 |
Formula | C29H38N4O4 |
CAS No. | 2234874-68-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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αvβ1 integrin-IN-2 2234874-68-9 Cytoskeletal Signaling Integrin inhibitor inhibit