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Anti-DKK1 Antibody (3D142) (Synonyms: dickkopf WNT signaling pathway inhibitor 1)
Catalog No. TMAY-00395 Copy Product Info
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Anti-DKK1 Antibody (3D142) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (3D142) can be used in ELISA,ELISA(Det).
Anti-DKK1 Antibody (3D142)
Copy Product Info🥰Excellent
Catalog No. TMAY-00395
Synonyms dickkopf WNT signaling pathway inhibitor 1
Anti-DKK1 Antibody (3D142) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (3D142) can be used in ELISA,ELISA(Det).
Anti-DKK1 Antibody
(3D142)
(3D142)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $69 | 7-10 days | 7-10 days | |
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DKK1 Antibody (3D142) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (3D142) can be used in ELISA,ELISA(Det). |
| Synonyms | dickkopf WNT signaling pathway inhibitor 1 |
| Ig Type | Mouse IgG2b |
| Clone | 3D142 |
| Reactivity | Human |
| Specificity | Human DKK-1 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Dkk1 (rhDkk1; TMPY-00775; NP_036374.1; Met 2-His266). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Dkk1 protein (TMPY-00775) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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