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Ajugol

Name: Ajugol
Brand: TargetMol
SKU: T3792
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3792Cas No. 52949-83-4

Alias Leonuride

Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).

Ajugol

🥰Excellent

Purity: 99.65%

Catalog No. T3792Alias LeonurideCas No. 52949-83-4

Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).

Pack Size	Price	Availability
2 mg	$36	In Stock
5 mg	$54	In Stock
10 mg	$77	In Stock
25 mg	$123	In Stock
50 mg	$179	In Stock
100 mg	$266	In Stock
200 mg	$395	In Stock
1 mL x 10 mM (in DMSO)	$60	In Stock

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Batch Information

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Purity:99.65%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).
Targets&IC50	T. brucei rhodesiense:29.3–73.0 ug/ml
Synonyms	Leonuride

Chemical Properties

Molecular Weight	348.35
Formula	C₁₅H₂₄O₉
Cas No.	52949-83-4
Smiles	[H][C@@]12C=CO[C@@H](O[C@]3([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@]1([H])[C@@](C)(O)C[C@H]2O
Relative Density.	1.57g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (114.83 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8707 mL	14.3534 mL	28.7068 mL	143.5338 mL
5 mM	0.5741 mL	2.8707 mL	5.7414 mL	28.7068 mL
10 mM	0.2871 mL	1.4353 mL	2.8707 mL	14.3534 mL
20 mM	0.1435 mL	0.7177 mL	1.4353 mL	7.1767 mL
50 mM	0.0574 mL	0.2871 mL	0.5741 mL	2.8707 mL
100 mM	0.0287 mL	0.1435 mL	0.2871 mL	1.4353 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc