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Anti-JAK1 Antibody (8S374)

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Catalog No. TMAH-00654

Anti-JAK1 Antibody (8S374) is an antibody targeting JAK1. Anti-JAK1 Antibody (8S374) can be used in ELISA, IHC.

Anti-JAK1 Antibody (8S374)

Anti-JAK1 Antibody (8S374)

😃Good
Catalog No. TMAH-00654
Anti-JAK1 Antibody (8S374) is an antibody targeting JAK1. Anti-JAK1 Antibody (8S374) can be used in ELISA, IHC.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$349 7-10 days
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Instruction Manual of Detection Antibody
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, IHC

Reactivity: Human
Ig Type
Rabbit IgG
Clone
8S374
Reactivity
Human
Verified Activity
IHC image of TMAH-00654 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
ELISA, IHC
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationEndomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundTyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human JAK1
Antigen Species
Human
Gene ID
3716
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cancer, Cell biology, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tyrosine-protein kinase JAK1Janus kinase 1 (JAK-1)JAK1BJAK1AJAK-1JAK1JAK 1
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