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Anti-ISL1 Antibody (9H190)

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Catalog No. TMAH-00639
Alias Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (9H190) is an antibody targeting ISL1. Anti-ISL1 Antibody (9H190) can be used in ELISA, WB.

Anti-ISL1 Antibody (9H190)

Anti-ISL1 Antibody (9H190)

😃Good
Catalog No. TMAH-00639Alias Islet-1, ISL 1, Insulin gene enhancer protein ISL-1
Anti-ISL1 Antibody (9H190) is an antibody targeting ISL1. Anti-ISL1 Antibody (9H190) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$208 7-10 days
100 μL$349 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, WB

Reactivity: Human
AliasIslet-1, ISL 1, Insulin gene enhancer protein ISL-1
Ig Type
Rabbit IgG
Clone
9H190
Reactivity
Human
Verified Activity
Western Blot
-Positive WB detected in: Hela whole cell lysate, SH-SY5Y whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate
-All lanes: ISL1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 40 kDa
-Observed band size: 39 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:5000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundDNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human Islet 1
Antigen Species
Human
Gene ID
3670
Uniprot ID
Biology Area
Neuroscience, Cardiovascular, Developmental biology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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