Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = <100 μM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 μM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 198.00 | |
5 mg | 35 days | $ 595.00 | |
10 mg | 35 days | $ 990.00 |
Description | 4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 μM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 μM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells. |
Molecular Weight | 582.853 |
Formula | C34H50O6Si |
CAS No. | 1214886-31-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
DMF: 5 mg/mL
You can also refer to dose conversion for different animals. More
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4-oxo-27-TBDMS Withaferin A 1214886-31-3 4oxo27TBDMS Withaferin A 4 oxo 27 TBDMS Withaferin A inhibitor inhibit