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BD 1008 dihydrobromide

Name: BD 1008 dihydrobromide
Brand: TargetMol
SKU: T21788
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21788Cas No. 138356-09-9

BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.

BD 1008 dihydrobromide

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Purity: 97.81%

Catalog No. T21788Cas No. 138356-09-9

BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$35	In Stock	In Stock
5 mg	$56	In Stock	In Stock
10 mg	$98	In Stock	In Stock
25 mg	$217	In Stock	In Stock
50 mg	$372	In Stock	In Stock
100 mg	$531	-	In Stock
1 mL x 10 mM (in DMSO)	$73	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:97.81%

Appearance:solid

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors.
Targets&IC50	σ1 receptor:2 nM(Ki)

Chemical Properties

Molecular Weight	463.08
Formula	C₁₅H₂₄Br₂Cl₂N₂
Cas No.	138356-09-9
Smiles	[H]Br.[H]Br.CN(CCC1=CC=C(Cl)C(Cl)=C1)CCN2CCCC2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 32.5 mg/mL (70.18 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1595 mL	10.7973 mL	21.5945 mL	107.9727 mL
5 mM	0.4319 mL	2.1595 mL	4.3189 mL	21.5945 mL
10 mM	0.2159 mL	1.0797 mL	2.1595 mL	10.7973 mL
20 mM	0.1080 mL	0.5399 mL	1.0797 mL	5.3986 mL
50 mM	0.0432 mL	0.2159 mL	0.4319 mL	2.1595 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc