Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM). AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 3,020.00 | |
50 mg | 10-14 weeks | $ 3,980.00 | |
100 mg | 10-14 weeks | $ 5,500.00 |
Description | AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM). AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe. |
Molecular Weight | 375.59 |
Formula | C24H41NO2 |
CAS No. | 2244425-65-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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AMG-315 2244425-65-6 DWN12088 HCl DWN-12088 dihydrochloride DWN-12088 hydrochloride AMG 315 AMG315 DWN 12088 HCl inhibitor inhibit