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Anti-EGFR Antibody (9Y91) (Synonyms: PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor recep...)

Catalog No. TMAY-00025 Copy Product Info
🥰Excellent
Anti-EGFR Antibody (9Y91) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (9Y91) can be used in ELISA,ICC/IF.

Anti-EGFR Antibody (9Y91)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00025
Synonyms PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (9Y91) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (9Y91) can be used in ELISA,ICC/IF.

Anti-EGFR Antibody
(9Y91)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EGFR Antibody (9Y91) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (9Y91) can be used in ELISA,ICC/IF.
SynonymsPIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Ig Type
Rabbit IgG
Clone
9Y91
Reactivity
Human
Specificity
Human EGFR
No cross-reactivity in ELISA with
Human ErbB2
Human ErbB3
Verified Activity
Immunofluorescence staining of EGFR in A431 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human EGFR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Cell membrane.
Application
Recommended Dose
ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-00742; NP_005219; Met 1-Ser 645).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAs a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human EGFR / HER1 / ErbB1 protein (TMPY-00742)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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