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Acevaltrate

Name: Acevaltrate
Brand: TargetMol
SKU: TJP2872
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TJP2872Cas No. 25161-41-5

Alias Acevaltratum, Acetoxyvaltrate

1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.

Acevaltrate

🥰Excellent

Purity: 99.94%

Catalog No. TJP2872Alias Acevaltratum, AcetoxyvaltrateCas No. 25161-41-5

Pack Size	Price	Availability
1 mg	$38	In Stock
5 mg	$89	In Stock
10 mg	$139	In Stock
25 mg	$278	In Stock
50 mg	$441	In Stock
100 mg	$649	In Stock
1 mL x 10 mM (in DMSO)	$98	In Stock

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Batch Information

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Purity:99.94%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.
Targets&IC50	COLO 320 cells:1-6 μM, GLC4 cells:1-6 μM
Synonyms	Acevaltratum, Acetoxyvaltrate

Chemical Properties

Molecular Weight	480.5
Formula	C₂₄H₃₂O₁₀
Cas No.	25161-41-5
Smiles	[H][C@]12[C@H](OC(=O)CC(C)C)OC=C(COC(C)=O)C1=C[C@H](OC(=O)CC(C)(C)OC(C)=O)[C@]21CO1
Relative Density.	1.26g/cm3
Color	White
Appearance	solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (260.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0812 mL	10.4058 mL	20.8117 mL	104.0583 mL
5 mM	0.4162 mL	2.0812 mL	4.1623 mL	20.8117 mL
10 mM	0.2081 mL	1.0406 mL	2.0812 mL	10.4058 mL
20 mM	0.1041 mL	0.5203 mL	1.0406 mL	5.2029 mL
50 mM	0.0416 mL	0.2081 mL	0.4162 mL	2.0812 mL
100 mM	0.0208 mL	0.1041 mL	0.2081 mL	1.0406 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc