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Faricimab (Synonyms: RG-7716, RG7716)

Catalog No. T78253 Copy Product Info
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Faricimab, a bispecific antibody targeting Angiopoietin-2 (Ang-2) and VEGF-A. Faricimab prevents retinal ischemia/reperfusion (I/R) injury and vascular leakage, cell death, and inflammation in sCNV mouse models, showing superior visual acuity improvement over ranibizumab for retinal diseases including w-AMD, DME, and RVO.

Faricimab

Copy Product Info
🥰Excellent
Catalog No. T78253
Synonyms RG-7716, RG7716

Faricimab, a bispecific antibody targeting Angiopoietin-2 (Ang-2) and VEGF-A. Faricimab prevents retinal ischemia/reperfusion (I/R) injury and vascular leakage, cell death, and inflammation in sCNV mouse models, showing superior visual acuity improvement over ranibizumab for retinal diseases including w-AMD, DME, and RVO.

Faricimab
Cas No. 1607793-29-2
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$645-In Stock
5 mg$1,690-In Stock
10 mg$2,6802-4 weeks2-4 weeks
25 mg$3,9902-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95% (SDS-PAGE); >95% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Faricimab, a bispecific antibody targeting Angiopoietin-2 (Ang-2) and VEGF-A. Faricimab prevents retinal ischemia/reperfusion (I/R) injury and vascular leakage, cell death, and inflammation in sCNV mouse models, showing superior visual acuity improvement over ranibizumab for retinal diseases including w-AMD, DME, and RVO.
In vivo
Faricimab (10 mg/kg, intraperitoneal injection, once a week, 1-5 weeks) can reduce spontaneous choroidal neovascularization (sCNV), lesion leakage area and subretinal Iba1+, CD11b+, CD45+ cell infiltration in JR5558 mice. [1]
SynonymsRG-7716, RG7716
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetANG2 & VEGFA
Chemical Properties
Molecular Weight146 kDa
Cas No.1607793-29-2
Antibody Information
IsotypeHuman IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover
Storage & Solubility Information
StorageStore at low temperature | Store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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