Shopping Cart
Remove All
Your shopping cart is currently empty
ATV041
Copy Product Info
😃Good
Catalog No. T82937Cas No. 2935937-67-8
ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity. The compound demonstrates a dose-dependent reduction in viral load, tissue damage, and virus-induced inflammation [1].
ATV041
Copy Product Info😃Good
Catalog No. T82937Cas No. 2935937-67-8
ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity. The compound demonstrates a dose-dependent reduction in viral load, tissue damage, and virus-induced inflammation [1].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ATV041, an orally active compound that combines features of Ibuprofen and nucleotide analogues, enhances the oral pharmacokinetic (PK) profile and tissue distribution, exhibiting anti-mouse hepatitis virus (MHV) activity. The compound demonstrates a dose-dependent reduction in viral load, tissue damage, and virus-induced inflammation [1]. |
| In vitro | The chemical compound ATV041 exhibits inhibitory activity against CCoV, FIPV, and TGEV with EC50 values of 1.406 µM, 7.34 µM, and 3.777 µM, respectively [1]. |
| In vivo | ATV041 (200 mg/kg; oral; single dose) distributes extensively and rapidly throughout the plasma, liver, lungs, and kidney tissues [1]. When administered orally in single doses of 10, 50, and 200 mg/kg, ATV041 inhibits viral replication in the liver and lungs in a dose-dependent manner. Additionally, ATV041 decreases the expression of inflammatory cytokines TNF-α, IL-1β, IL-6, IFN-γ, and CXCL10, leading to amelioration of tissue damage [1]. |
| Molecular Weight | 479.53 |
| Formula | C25H29N5O5 |
| Cas No. | 2935937-67-8 |
| Smiles | C(#N)[C@]1(O[C@H](COC(C(C)C2=CC=C(CC(C)C)C=C2)=O)[C@@H](O)[C@H]1O)C=3N4C(=CC3)C(N)=NC=N4 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy ATV041 | purchase ATV041 | ATV041 cost | order ATV041 | ATV041 chemical structure | ATV041 in vivo | ATV041 in vitro | ATV041 formula | ATV041 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.