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Anti-ITGB2 Antibody (9Z591)
😃Good
Catalog No. TMAH-00650
Alias p95, OTTHUMP00000115282, OTTHUMP00000115281, OTTHUMP00000115280, OTTHUMP00000115279, OTTHUMP00000115278, MFI7, MF17, Macrophage antigen 1 (mac1) beta, MAC1, MAC 1, Lymphocyte function associated antigen 1, LFA1, LFA 1, Leukocyte cell adhesion molecule CD18, LCAMB, LAD, ITGB 2, ITB2_HUMAN, Integrin beta-2, Integrin beta chain beta 2, Integrin beta 2, Complement receptor C3 subunit beta, Complement component 3 receptor 3 and 4 subunit, Cell surface adhesion glycoproteins LFA-1/CR3/p150, CD18, CD 18, 95 subunit beta
Anti-ITGB2 Antibody (9Z591) is an antibody targeting ITGB2. Anti-ITGB2 Antibody (9Z591) can be used in ELISA, FC.
Anti-ITGB2 Antibody (9Z591)
Anti-ITGB2 Antibody (9Z591)
😃Good
Catalog No. TMAH-00650Alias p95, OTTHUMP00000115282, OTTHUMP00000115281, OTTHUMP00000115280, OTTHUMP00000115279, OTTHUMP00000115278, MFI7, MF17, Macrophage antigen 1 (mac1) beta, MAC1, MAC 1, Lymphocyte function associated antigen 1, LFA1, LFA 1, Leukocyte cell adhesion molecule CD18, LCAMB, LAD, ITGB 2, ITB2_HUMAN, Integrin beta-2, Integrin beta chain beta 2, Integrin beta 2, Complement receptor C3 subunit beta, Complement component 3 receptor 3 and 4 subunit, Cell surface adhesion glycoproteins LFA-1/CR3/p150, CD18, CD 18, 95 subunit beta
Anti-ITGB2 Antibody (9Z591) is an antibody targeting ITGB2. Anti-ITGB2 Antibody (9Z591) can be used in ELISA, FC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 197 € | 7-10 days | |
| 100 μL | 330 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ITGB2 Antibody (9Z591) is an antibody targeting ITGB2. Anti-ITGB2 Antibody (9Z591) can be used in ELISA, FC. |
| Alias | p95, OTTHUMP00000115282, OTTHUMP00000115281, OTTHUMP00000115280, OTTHUMP00000115279, OTTHUMP00000115278, MFI7, MF17, Macrophage antigen 1 (mac1) beta, MAC1, MAC 1, Lymphocyte function associated antigen 1, LFA1, LFA 1, Leukocyte cell adhesion molecule CD18, LCAMB, LAD, ITGB 2, ITB2_HUMAN, Integrin beta-2, Integrin beta chain beta 2, Integrin beta 2, Complement receptor C3 subunit beta, Complement component 3 receptor 3 and 4 subunit, Cell surface adhesion glycoproteins LFA-1/CR3/p150, CD18, CD 18, 95 subunit beta |
| Ig Type | mIgG2a |
| Clone | 9Z591 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing THP-1 cells stained with TMAH-00650 (red line) at 1:100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-mouse IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was mouse IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, FC |
| Recommended Dose | FC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages. In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ITGB2 Protein |
| Antigen Species | Human |
| Gene ID | 3689 |
| Uniprot ID | |
| Biology Area | Immunology, Signal transduction, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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