Shopping Cart

Your shopping cart is currently empty

Ligustroside (Synonyms: Ligstroside)

Name: Ligustroside
Brand: TargetMol
SKU: TN1871
Price: 198 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. TN1871 Copy Product Info

Purity: 99.26%

🥰Excellent

Ligustroside is a natural product of phenolic glycosides from olive plants, which has antioxidant and anti-inflammatory activities. Ligustroside can up-regulate the mRNA expression of SIRT1, CREB1 and GPx1 in SH-SY5Y-APP695 cells. At the same time, the production of nitric oxide (NO) was significantly inhibited in RAW264.7 macrophages stimulated by lipopolysaccharide (LPS). Ligustroside has potential application value in cardiovascular and metabolic diseases related research.

Ligustroside

Copy Product Info

🥰Excellent

Catalog No. TN1871

Synonyms Ligstroside

Cas No. 35897-92-8

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
1 mg	$198	-	In Stock
5 mg	$562	-	In Stock
10 mg	$925	-	In Stock
25 mg	$1,390	-	In Stock
50 mg	$1,870	-	In Stock
100 mg	$2,520	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:99.26%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ligustroside is a natural product of phenolic glycosides from olive plants, which has antioxidant and anti-inflammatory activities. Ligustroside can up-regulate the mRNA expression of SIRT1, CREB1 and GPx1 in SH-SY5Y-APP695 cells. At the same time, the production of nitric oxide (NO) was significantly inhibited in RAW264.7 macrophages stimulated by lipopolysaccharide (LPS). Ligustroside has potential application value in cardiovascular and metabolic diseases related research.
Targets&IC50	SKBR3 cells:> 20 μM
In vitro	Hydrolysis of oleoside-type secoiridoid glucosides, oleuropein (1) and Ligustroside (2), in the presence of β-glucosidase provided their aglycones, named (5S,8R,9S)-7-3,4-dihydroxyphenethyl elenolate (3) and (5S,8R,9S)-7-4-hydroxyphenethyl elenolate (4), respectively. The structures of 3 and 4 were identified by spectroscopic means and optical rotation measurements[1]
Synonyms	Ligstroside

Chemical Properties

Molecular Weight	524.51
Formula	C₂₅H₃₂O₁₂
Cas No.	35897-92-8
Smiles	C(C(OCCC1=CC=C(O)C=C1)=O)[C@H]2/C(=C\C)/[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(OC)=O
Relative Density.	1.44 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (190.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9065 mL	9.5327 mL	19.0654 mL	95.3271 mL
5 mM	0.3813 mL	1.9065 mL	3.8131 mL	19.0654 mL
10 mM	0.1907 mL	0.9533 mL	1.9065 mL	9.5327 mL
20 mM	0.0953 mL	0.4766 mL	0.9533 mL	4.7664 mL
50 mM	0.0381 mL	0.1907 mL	0.3813 mL	1.9065 mL
100 mM	0.0191 mL	0.0953 mL	0.1907 mL	0.9533 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc