Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, (Z)-4EGI-1 possesses anticancer activity[1][2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 119.00 | |
5 mg | 5 days | $ 198.00 | |
10 mg | 5 days | $ 376.00 | |
50 mg | 6-8 weeks | $ 789.00 | |
100 mg | 6-8 weeks | $ 1,190.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 226.00 |
Description | (Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, (Z)-4EGI-1 possesses anticancer activity[1][2]. |
Targets&IC50 | eIF4E:43.5 μM (IC50), eIF4E:8.74 μM (Kd) |
Molecular Weight | 451.28 |
Formula | C18H12Cl2N4O4S |
CAS No. | 901787-88-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (110.80 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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(Z)-4EGI-1 901787-88-0 (Z)4EGI1 (Z) 4EGI 1 4EGI-1 inhibitor inhibit