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SB-216

🥰Excellent
Catalog No. T60757Cas No. 2756818-39-8

SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].

SB-216

SB-216

🥰Excellent
Purity: 99.70%
Catalog No. T60757Cas No. 2756818-39-8
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].
Pack SizePriceAvailabilityQuantity
1 mg$49In Stock
5 mg$118In Stock
10 mg$198In Stock
25 mg$349In Stock
50 mg$499In Stock
100 mg$690In Stock
1 mL x 10 mM (in DMSO)$135In Stock
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.70%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, breast cancer, and lung cancer [1].
In vitro
SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer. SB-216 can be used for cancer research[1].
Chemical Properties
Molecular Weight310.35
FormulaC17H18N4O2
Cas No.2756818-39-8
SmilesCOc1ccc2N(CC(=O)Nc2c1)c1nc(C)nc2CCCc12
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 58.5 mg/mL (188.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2222 mL16.1108 mL32.2217 mL161.1084 mL
5 mM0.6444 mL3.2222 mL6.4443 mL32.2217 mL
10 mM0.3222 mL1.6111 mL3.2222 mL16.1108 mL
20 mM0.1611 mL0.8055 mL1.6111 mL8.0554 mL
50 mM0.0644 mL0.3222 mL0.6444 mL3.2222 mL
100 mM0.0322 mL0.1611 mL0.3222 mL1.6111 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tubulin polymerizationMicrotubuleAssociatedMicrotubule Associated
Related Tags: buy SB-216 | purchase SB-216 | SB-216 cost | order SB-216 | SB-216 chemical structure | SB-216 in vitro | SB-216 formula | SB-216 molecular weight
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