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Anti-ST2/IL-1 RL1 Antibody (3X618)
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Catalog No. TMAY-00263
Alias interleukin 1 receptor-like 1
Anti-ST2/IL-1 RL1 Antibody (3X618) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (3X618) can be used in ELISA.
Anti-ST2/IL-1 RL1 Antibody (3X618)
Anti-ST2/IL-1 RL1 Antibody (3X618)
😃Good
Catalog No. TMAY-00263Alias interleukin 1 receptor-like 1
Anti-ST2/IL-1 RL1 Antibody (3X618) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (3X618) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Chemical Properties
| Description | Anti-ST2/IL-1 RL1 Antibody (3X618) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (3X618) can be used in ELISA. |
| Alias | interleukin 1 receptor-like 1 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 3X618 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 extracellular domain (rh IL1RL1; Met 1-Phe 328NP_003847.2). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines. |
| Conjucates | Unconjugated |
| Others Formats | HRP |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human IL1RL1 protein (TMPY-01359) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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