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Anti-BAG3 Antibody (8D844)
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Catalog No. TMAH-00102
Alias MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3
Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA, WB, IHC.
Anti-BAG3 Antibody (8D844)
Anti-BAG3 Antibody (8D844)
😃Good
Catalog No. TMAH-00102Alias MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3
Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA, WB, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA, WB, IHC. |
| Alias | MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3 |
| Ig Type | Rabbit IgG |
| Clone | 8D844 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate -All lanes: BAG3 antibody at 0.73μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 62 KDa -Observed band size: 80 KDa 2. IHC image of TMAH-00102 diluted at 1:73.75 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Application | ELISA, WB, IHC |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human BAG3 |
| Antigen Species | Human |
| Gene ID | 9531 |
| Uniprot ID | |
| Biology Area | Cell Biology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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