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Anti-BAG3 Antibody (8D844) (Synonyms: MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bc...)

Catalog No. TMAH-00102 Copy Product Info
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Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA,IHC,WB.

Anti-BAG3 Antibody (8D844)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00102
Synonyms MFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3

Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA,IHC,WB.

Anti-BAG3 Antibody
(8D844)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BAG3 Antibody (8D844) is an antibody targeting BAG3. Anti-BAG3 Antibody (8D844) can be used in ELISA,IHC,WB.
SynonymsMFM6, Docking protein CAIR-1, Docking protein CAIR 1, CAIR 1, BIS, Bcl-2-binding protein Bis, Bcl-2-associated athanogene 3, BCL2 binding athanogene 3, BCL2 associated athanogene 3, Bcl 2 binding protein, BAG family molecular chaperone regulator 3, BAG 3
Ig Type
Rabbit IgG
Clone
8D844
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
-All lanes: BAG3 antibody at 0.73μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 62 KDa
-Observed band size: 80 KDa
2. IHC image of TMAH-00102 diluted at 1:73.75 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Cytoplasm.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCo-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human BAG3
Antigen Species
Human
Gene Name
BAG3
Gene ID
Uniprot ID
Biology Area
Cell Biology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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