Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 78.00 | |
10 mg | In stock | $ 119.00 | |
25 mg | In stock | $ 239.00 | |
50 mg | In stock | $ 355.00 | |
100 mg | In stock | $ 527.00 |
Description | NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders. |
Targets&IC50 | rNaV1.6:9.8 μM, Nav1.2 (human):24.4 μM |
In vitro | NaV1.2/1.6 channel blocker(Compound 13)inhibits 48.5% and 34.0% of NaV1.6 and NaV1.2 sodium currents, respectively, in HEK 293 cells stably expressing rat NaV1.6 and human NaV1.2 isoforms at concentrations ranging from 1 to 100 μM [1]. |
Molecular Weight | 258.34 |
Formula | C14H14N2OS |
CAS No. | 1199944-04-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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NaV1.2/1.6 channel blocker-1 1199944-04-1 Membrane transporter/Ion channel Sodium Channel inhibitor inhibit