Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 93.00 | |
5 mg | 35 days | $ 290.00 | |
10 mg | 35 days | $ 533.00 | |
25 mg | 35 days | $ 1,210.00 |
Description | BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1 |
In vivo | In vivo, BHBM (1.2 mg/kg per day) increases survival in a mouse model of C. neoformans infection. |
Molecular Weight | 333.18 |
Formula | C15H13BrN2O2 |
CAS No. | 302807-84-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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BHBM 302807-84-7 inhibitor inhibit