Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), demonstrating modest affinity with a binding constant of approximately 80 μM for the KDM4A-Tudor domain. It effectively inhibits the binding of H3K4Me3 to the Tudor domain in cellular contexts, displaying an EC50 value of 105 μM. This compound holds potential for anticancer research applications [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,520.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), demonstrating modest affinity with a binding constant of approximately 80 μM for the KDM4A-Tudor domain. It effectively inhibits the binding of H3K4Me3 to the Tudor domain in cellular contexts, displaying an EC50 value of 105 μM. This compound holds potential for anticancer research applications [1]. |
Molecular Weight | 245.36 |
Formula | C16H23NO |
CAS No. | 2230475-63-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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KDM4-IN-4 2230475-63-3 inhibitor inhibit