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1-(8-carbamimidamidooctyl)guanidine 2HCl

🥰Excellent
Catalog No. T50091Cas No. 25303-05-3
Alias 1,1'-(Octane-1,8-diyl)diguanidine 2HCl, 1-(8-carbamimidamidooctyl)guanidine dihydrochloride

1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride is a synthetic opioid peptide derived from the natural opioid peptide enkephalin. It is a potent agonist of the mu-opioid receptor (MOR) with a Ki of 0.14 nM, making it one of the most potent MOR agonists known to date.

1-(8-carbamimidamidooctyl)guanidine 2HCl

1-(8-carbamimidamidooctyl)guanidine 2HCl

🥰Excellent
Purity: 95.00%
Catalog No. T50091Alias 1,1'-(Octane-1,8-diyl)diguanidine 2HCl, 1-(8-carbamimidamidooctyl)guanidine dihydrochlorideCas No. 25303-05-3
1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride is a synthetic opioid peptide derived from the natural opioid peptide enkephalin. It is a potent agonist of the mu-opioid receptor (MOR) with a Ki of 0.14 nM, making it one of the most potent MOR agonists known to date.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$60In StockIn Stock
5 mg$139In StockIn Stock
10 mg$209In StockIn Stock
25 mg$333In StockIn Stock
50 mg$470In StockIn Stock
100 mg$638In StockIn Stock
200 mg$833In StockIn Stock
1 mL x 10 mM (in DMSO)$135In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:95.00%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride is a synthetic opioid peptide derived from the natural opioid peptide enkephalin. It is a potent agonist of the mu-opioid receptor (MOR) with a Ki of 0.14 nM, making it one of the most potent MOR agonists known to date.
Synonyms1,1'-(Octane-1,8-diyl)diguanidine 2HCl, 1-(8-carbamimidamidooctyl)guanidine dihydrochloride
Chemical Properties
Molecular Weight301.26
FormulaC10H26Cl2N6
Cas No.25303-05-3
SmilesNC(NCCCCCCCCNC(N)=N)=N.[H]Cl.[H]Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (165.97 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3194 mL16.5970 mL33.1939 mL165.9696 mL
5 mM0.6639 mL3.3194 mL6.6388 mL33.1939 mL
10 mM0.3319 mL1.6597 mL3.3194 mL16.5970 mL
20 mM0.1660 mL0.8298 mL1.6597 mL8.2985 mL
50 mM0.0664 mL0.3319 mL0.6639 mL3.3194 mL
100 mM0.0332 mL0.1660 mL0.3319 mL1.6597 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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