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Thiamine disulfide (Alias: TDS, Daiomin, Algoneurina)

Name: Thiamine disulfide
Brand: TargetMol
SKU: T20062
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T20062 Copy Product Info

Purity: 99.81%

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Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.

Thiamine disulfide

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Catalog No. T20062

Alias TDS, Daiomin, Algoneurina

Cas No. 67-16-3

Pack Size	Price	USA Stock	Global Stock	Quantity
1 g	$34	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.81%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Thiamine disulfide AI Summary

Thiamine disulfide shows bioactivity in qHTS assays for identifying compounds that block the entry of the Ebola virus. The reported AC50 values range from 3162.3 nM to 8.913 μM. At these concentrations, the compound demonstrates a potential inhibitory effect on the entry mechanism of the Ebola virus..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing enzymes.
Synonyms	TDS, Daiomin, Algoneurina

Chemical Properties

Molecular Weight	562.71
Formula	C₂₄H₃₄N₈O₄S₂
Cas No.	67-16-3
Smiles	C\C(N(Cc1cnc(C)nc1N)C=O)=C(\CCO)SS\C(CCO)=C(\C)N(Cc1cnc(C)nc1N)C=O
Relative Density.	1.1966 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (444.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (8.89 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7771 mL	8.8856 mL	17.7711 mL	88.8557 mL
5 mM	0.3554 mL	1.7771 mL	3.5542 mL	17.7711 mL
10 mM	0.1777 mL	0.8886 mL	1.7771 mL	8.8856 mL
20 mM	0.0889 mL	0.4443 mL	0.8886 mL	4.4428 mL
50 mM	0.0355 mL	0.1777 mL	0.3554 mL	1.7771 mL
100 mM	0.0178 mL	0.0889 mL	0.1777 mL	0.8886 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc